Active B Complex (60 Capsules)

Active B Complex (60 Capsules)

Regular price $28.95 Sale

Feature Summary:

Active B Complex provides the most biologically active forms and clinically relevant doses of a unique B vitamin combination. Quatrefolic folate provides (6S)-5-Methyltetrahydrofolate acid (MTHF), the active form of folate at the cellular level, the form found in circulation, and the only form able to cross the blood brain barrier. This form of folate bypasses enzymatic conversion by methylene tetrahydrofolate reductase (MTHFR), an enzyme with common genetic polymorphisms known to impair activity. Quatrefolic acid administration has been associated with higher peak (6S)-5-MTHF levels than both folic acid and calcium 5-MTHF, with higher plasma folate levels even in those with high functioning MTHFR polymorphisms.1,2

In addition to superior folate bioavailability, Active B Complex contains superior forms of each B vitamin. Benfotiamine is a lipid soluble form of vitamin B1 with higher bioavailability than thiamine, used in the treatment of diabetic neuropathy because it blocks several hyperglycemic pathways and prevents endothelial dysfunction.3,4,5 Riboflavin 5’-phospate and pyridoxal 5’-phosphate (PLP) are biologically active forms of B2 and B6  PLP being the most important member of the B6 group, and is the active coenzyme for more than 100 enzymes, bypassing hepatic conversion to an active form.



  • Provides the natural and most bioactive form of folate, Quatrefolic folate (6S)-5-MTHF, with no synthetic or racemic components
  • Quatrefolic folate supplementation has a greater increase in plasma folate compared to folic acid and calcium 5-MTHF
  • Contains most bioactive and bioavailable forms of each B vitamin, including methylcobalamin (B12), riboflavin 5’-phosphate (B2), and pyridoxal 5’-phosphate (B6)
  • Broad spectrum B complex, with inositol, biotin, and choline
  • Suitable for vegetarians/vegans


Each Vegetarian Capsule Contains:

Vitamin B1 (Thiamine Hydrochloride) - 25 mg
Benfotiamine - 10 mg
Vitamin B2 (Riboflavin 5-Phosphate Sodium) -10 mg
Niacin (Inositol Hexanicotinate) - 100 mg
Pantothenic Acid (Calcium d-Pantothenate) - 100 mg
Vitamin B6 (Pyridoxal 5-Phosphate) - 25 mg
Vitamin B12 (Methylcobalamin) - 500 mcg
Quatrefolic Folate ((6S)-5-Methyltetrahydrofolate Acid, Glucosamine Salt) - 400 mcg
Biotin - 250 mcg
Choline (Citrate) - 50 mg
Inositol - 25 mg


Non-Medicinal Ingredients:

Microcrystalline cellulose, vegetarian capsule (carbohydrate gum [cellulose], purified water), vegetable grade magnesium stearate (lubricant).


Serving Size: 1 Vegetarian Capsule
Servings per Container: 60